Research by the world-class Spanish scientist Inaigo Saenz de Tejada into a THIRD system for erections – based on endothelium-derived hyperpolarizing factor (EDHF) – shows promise for developing new agents for supporting erections (LINK HERE). His group has done research with the drug calcium dobesilate, which seemed to provide benefits even when other systems – based on nitric oxide – were inhibited (as in men with diabetes). They propose a combination of approaches, which is likely to be the treatment of the future, at least for diabetic men (LINK HERE).
Now, if only I could find an herb that is an EDHF…then that would be something to add to Viagra/Cialis for increased benefits. I did a search for this but nothing showed up in the medical literature.