Excessive TNF-alpha levels are associated with ED – so does reducing them help fight ED?

Here is a post from another blog that might help:
A while ago I was doing some experiments taking herbal and vitamin TNF-alpha inhibitors (for anti-inflammatory purposes), and noticed that while I took these, I had the hardest erections I’d seen for ages. Sometimes just spontaneous ones, like being a teenager.

On checking this out, I found that there is a link between erectile dysfunction and high TNF-alpha:

TNF-alpha knockout mice have increased corpora cavernosa relaxation

Since TNF-alpha may arise from chronic low level infection, here we see yet again that there is a link between a human health condition — in this case erectile dysfunction — and pathogenic microbes. 

Perhaps those people with higher microbial loads in their bodies will have higher TNF-alpha levels. And such people may therefore have less erection strength. (Actually, this might not be a bad thing from an evolutionary perspective, as I guess it might tend to prevent procreation from men that have high microbial loads in their bodies — and so would not be strong and fit fathers).

Anyway, for anyone that has some underlying chronic inflammation in their body (perhaps due to an infection-linked health conditions like CFS, lupus, IBS, etc), consider that this may be causing a degree of erectile dysfunction.

Here is a list of TNF-alpha inhibitors (in no particular order) that may remedy this erectile dysfunction:



The following supplements DECREASE production of TNF-alpha

Cat’s claw herb – a remarkably potent inhibitor of TNF-alpha production.

5-Loxin” extract from Indian frankincense (Boswellia serrata) is a very potent inhibitor of TNF-alpha.

Acetylcholine significantly inhibits the release of TNF-alpha (L-carnitine can boost acetylcholine).

N-acetyl-L-cysteine
Astragalus
Burdock (Arctium lappa) — Arctigenin extract
Ginger
Chondroitin sulfate
Evening primrose oil (GLA converts to Prostaglandin E1, which suppresses TNF-alpha)
Devil’s claw
Curcumin
Milk thistle
Alpha lipoic acid
Allicin (from garlic)
Stinging nettle leaf (Urtica dioica)
Magnesium
Vitamin C
EGCG (green tea extract)
Vitamin E 
Tea tree oil
Ashwagandha (Withania somnifera)
Rehmannia root
Coptis root
Anethole (in fennel)
Frankincense
Xylitol
Fish Oil (Omega-3)
Oxymatrine
Artesunate
Dietary fiber 
Niacinamide
Andrographolide (from Andrographis paniculata)
Olmesartan (Benicar) 
Quinine
Naltrexone
Deprenyl
Azithromycin
Royal jelly
Oregano
Gingko
Licorice
Clove
Q10

The following INCREASE production of TNF-alpha

Reishi mushroom
Rhodiola rosea
Elderberry 
Chlorella
Spirulina
Ginseng
Aged garlic extract
Dandelion root
Honey
Chocolate
Echinacea
Silica
Lactoferrin
Biotin deficiency up-regulates TNF-alpha production in murine macrophages


Note that in my TNF-alpha reduction experiments, I used a good 10 or 12 of these various different supplements at the same time, including the more potent ones like cat’s claw, and ac