Here’s another avenue I’m following for better erections…dimethylarginine dimethylaminohydrolase (DDAH) is an enzyme that degrades asymmetric dimethylarginine (ADMA), which inhibits the production of nitric oxide synthase. Why should you care?

Because nitric oxide synthase takes a nitrogen atom from L-arginine, producing nitric oxide (NO), so that NO can activate cGMP and cause blood vessels in the penis to relax, so blood can come in and you can get an erection.

In certain health problems – such as high levels of homocysteine (homocysteinemia) – the evil ADMA is more likely to impair the release of NO. Therefore, it is reasonable to assume these elements play a role in erectile dysfunction.

DDAH is a perfect drug for supporting erections. In a mouse model, mice with high levels of DDAH decreased levels of ADMA by 50%, which was associated with a significant increase in nitric oxide synthase activity. They also had healthier blood vessels.

Has DDAH been explored as an ED treatment? Are there any herbs that mimic the effects of DDAH? I haven’t found any.